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Life in the Lab

May 3, 2023

Hidden behavioral fingerprints in epilepsy

Tilo Gschwind, Ayman Zeine, Ivan Raikov, ..., Lori L. Isom, Sandeep Robert Datta, Ivan Soltesz (2023)

Hidden behavioral fingerprints in epilepsy

Neuron 111, 1–13

Gschwind et al. show that machine learning-assisted behavioral analysis allows an unbiased assessment of epilepsy in animal models. The automated identification of behavioral phenotypes, including anti-epileptic drug responses, during the readily available inter-ictal periods bears great potential to accelerate rigorous, reproducible preclinical research into epilepsies.

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HISTORY SHOWS AGAIN AND AGAIN HOW NATURE POINTS OUT THE FOLLY OF MEN – “GODZILLA,” BLUE OYSTER CULT

Sandeep Robert Datta, MD, Ph.D Department of Neurobiology Harvard Medical School